Great animation can delight children or adults; truly great animation may delight both. But Tokyo Godfathers seems unlikely to enthrall either -- or be remembered much past the flicker of its final cel.
Kon deserves credit for attempting to animate a genre that has historically been best served by live action. The effort isn't entirely successful, but for an industry that rarely seeks to break free of tradition, that's already a quantum leap.
As visually accomplished as Tokyo Godfathers is, the story is the most primitive form of drama, one that counts on improbable coincidence to propel the story to its sudden, implausibly symbolic conclusion.