"Desperate Housewives" heart-throb Jesse Metcalfe has signed a deal with Fox to play the lead role in their romantic comedy "John Tucker." The Hollywood Reporter indicates that the movie will be about a "heartthrob whose serial cheating leads three ex-girlfriends to seek revenge by setting him up to fall for the new girl in town, just so that she can dump him and break his heart."

Veteran filmmaker Betty Thomas ("Private Parts," "I Spy") will be in the director's chair, and she'll be working from a screenplay by sitcom scribe Jeff Lowell.