Season Two of Grey's Anatomy initally aired on September 25 2005 with the premiere episode on ABC and ended on May 15, 2006 with the season finale. The season comprises of 27 episodes.
The second season saw the contination of the internship of Meredith Grey and her fellow residents Cristina, Izzie, Alex and George.
The season featured 10 actors credited in a starring capacity. All of the first season cast members returned and were credited for the full season. Kate Walsh, who guest starred in the first season finale, joined the main cast in the series' seventh episode after appearing under a 'Special Guest Star' credit for the first six episodes.
Season stars Pompeo, Oh, Heigl, Chambers, Knight, Pickens Jr, Walsh, Washington and Dempsey appear in all 27 second season episodes.
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