David S. Goyer Director, Screenwriter, Producer Wesley Snipes Blade Actor, Producer Kris Kristofferson Abraham Whistler Actor Jessica Biel Abigail Whistler Actor Ryan Reynolds Hannibal King Actor Parker Posey Danica Actor Dominic Purcell Dracula, Drake Actor John Michael Higgins Dr. Edgar Vance Actor James Remar Ray Cumberland Actor Eric Bogosian Bentley Tittle Actor Patton Oswalt Hedges Actor Callum Keith Rennie Asher Actor Natasha Lyonne Sommerfield Actor Mark Berry Chief Martin Vreede Actor Steve Braun FBI Agent Wilson Hale Actor Triple H Jarko Grimwood Actor Avi Arad Producer, Executive Producer Peter Frankfurt Producer Lynn Harris Producer Cale Boyter Executive Producer Toby Emmerich Executive Producer Stan Lee Executive Producer Gabriel Beristain Cinematographer Howard E. Smith Film Editor Conrad Smart Film Editing Ramin Djawadi Original Music RZA Original Music Chris Gorak Production Design Erin Fraser Art Director Patrick Banister Art Director, Art Director Eric Fraser Art Director Ted Kuchera Set Decoration, Set Designer Laura Jean Shannon Costume Design Ronnie Yeskel Casting Patrick Ramsay Sound George A. Grieve Unit Production Manager Pete Whyte First Assistant Director Vic Armstrong Second Unit Director