A doctor has developed an amazing new serum, one of those lovely glowing green liquids that looks just like the re-agent in Re-Animator. Our dear doctor is hired by a paralysed, badly burnt millionaire to use this wonderful new serum to help him. The serum will regenerate any damaged cells, and thankfully has no side effects. Oh and if the improper dosage is given it causes intense hunger and if more serum has been given than needed by the body the serum will continue to "perfect the host at a cellular level" and the hunger will drive the host to eat anything nearby which will then start to mutate the host into whatever it has eaten. Right so no side effects then. Unfortunately like all films with glowing green serums things are going to turn out badly. Our millionaire decides that the only way to see if the serum works is to test it on the doctor, and unluckily for him (and several other people) he doesn't get the right dosage. Oops. As I'm sure you've already guessed when he starts getting peckish it's not a cheese sandwich on the menu. Enter Tom Sizemore and a few unknowns as a maintenance crew who happen to be working in the same tunnels that the doctor ends up in. Throw in a few henchmen, sorry henchpeople of the millionaire and things start to get interesting.
The idea of the serum isn't too bad, and with a bigger budget and better effects could have made a good film, although the film they've created isn't too bad. The effects look ok, but don't really take advantage of the whole metamorphosis thing.