This low budget film from director/writer Debra Granik, who is also responsible for her latter "Winter's Bone", absolutely hit the mark. "Down to the Bone" is a vivid portrayal of drug abuse and family that boasts a stellar performance by Vera Farmiga. What sometimes appears slow and prodding, turns out to be calculated and striking. The film appeared to be shot using grainy handhelds; a most likely result of working with a shoestring budget. The visual appeal might not be there but hang in there, as the story and performances are topnotch.