Zachary Quinto Dr. Oliver Thredson Actor Joseph Fiennes Monsignor Timothy Howard Actor Sarah Paulson Lana Winters Actor Evan Peters Kit Walker Actor Lily Rabe Sister Mary Eunice Actor Lizzie Brocheré Grace Actor James Cromwell Dr. Arthur Arden Actor Jessica Lange Sister Jude Actor Clea Duvall Wendy Peyser Guest Star Britne Oldford Alma Walker Guest Star Barbara Tarbuck Mother Superior Claudia Guest Star Jill Marie Jones Pandora Guest Star Naomi Grossman Pepper Guest Star Kasey Mahaffy Father James Guest Star Matthew John Armstrong Detective Byers Guest Star Joel McKinnon Miller Detective Connors Guest Star Jennifer Holloway Barb Guest Star Vanessa Mizzone Lois Guest Star Mary-Pat Green Nun 1 Guest Star Gwynyth Walsh Dr. Stevens Guest Star Tacey Adams Sister Colette Guest Star Mark Engelhardt Carl Guest Star Meg Wolf Neo-Natal Nurse Guest Star Tom Virtue Reporter 1 Guest Star Dean Cameron Reporter 2 Guest Star James Calvert Reporter 3 Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Dante Di Loreto Executive Producer Tim Minear Executive Producer