Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Desmond Harrington Michael Actor Jordan Gelber M.E. Hawes Guest Star Rosanny Zayas Valentina Duran Guest Star Luis Antonio Ramos Father Cantu Guest Star Elena Hurst Detective Scandrick Guest Star Mike Cerveris Councilman Vucelich Guest Star John Dossett Treadwell Guest Star Anne L. Nathan Moira Baker Guest Star Francisco Burgos Cerio Cristobal Guest Star Jason Alan Carvell Detective Mori Guest Star Jorge Luna Cop 1 Guest Star Joseph Castillo-Midyett Cop 2 Guest Star Beth Fowler Anxious Woman Guest Star Merritt Janson Mallory Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Sherman Li Writer Christine Moore Director