A hard days night


Episode Info

It's a grueling and eventful first 48 hours for the new crop of surgical interns at Seattle Grace Hospital in the debut episode of Grey's Anatomy. Among the newcomers are Meredith Grey (Ellen Pompeo), still struggling to emerge from the shadow of her celebrated surgeon mother Ellis Grey (Kate Burton); fiercely competitive Stanford grad Cristina Yang (Sandra Oh), who will in time become Meredith's best friend; former fashion model Isobel "Izzie" Stevens (Katherine Heigl), a bit put off that she's no longer the sole center of attention; amiable, naïve George O'Malley (T.R. Knight); and Alex Karev (Justin Chambers), who wastes no time proving himself to be a pompous jerk. After a pep talk from chief surgeon Richard Webber (James Pickens Jr.), the interns are placed in the not-so-tender care of supervising doctor Miranda Bailey (Chandra Wilson), also known as "The Nazi" for reasons that become instantly obvious. During their two-day shakedown cruise, the rookies come face to face with the harsh realities of hospital life, with Meredith tending to a girl suffering from seizures, George enduring his first appendectomy, and Cristina finds that it's no picnic workiing under veteran surgeon Preston Burke (Isaiah Washington). But the biggest shock of all is reserved for Ellis, when she discovers that her handsome "one-night stand" from the previous evening happens to be her new boss, Dr. Derek Shepherd (Patrick Dempsey)! Peter Horton received an Emmy nomination for his direction of this inaugural episode.


Ellen Pompeo
as Meredith Grey
Sandra Oh
as Cristina Yang
Katherine Heigl
as Izzie Stevens
T.R. Knight
as George O'Malley
Justin Chambers
as Alex Karev
Chandra Wilson
as Miranda Bailey
Patrick Dempsey
as Derek Shepherd
Isaiah Washington
as Preston Burke
James Pickens Jr.
as Richard Webber
Sean Palmer
as Intern #3
Brad Pennington
as Radiologist
Sara Ramirez
as Callie Torres
Kevin Mckidd
as Owen Hunt
Jessica Capshaw
as Arizona Robbins
Jesse Williams
as Jackson Avery
Sarah Drew
as April Kepner
Jerrika Hinton
as Stephanie Edwards
Caterina Scorsone
as Amelia Shepherd
Kelly J. McCreary
as Margaret "Maggie" Pierce
Gregory Erff
as Mr. Jones
Richard Gilbert-Hill
as Small Town Doc
Robbie Troy
as Ms. Bryce
Kathleen M. Darcy
as Anestheseologist
Moe Irvin
as Tyler Christian
Randall Arney
as Mr. Bryce
Josh Bywater
as Intern #1
Grinnell Morris
as Intern #4
Kate Burton
as Ellis Grey
Billy Wood
as Senior Resident
David Vegh
as Tony Savitch
Laura Carson
as Gloria Savitch
Skyler Shaye
as Katie Bryce
Show More Cast

A hard days night Photos