After the unsolved murder of his wife, Adrian Monk develops obsessive-compulsive disorder, which includes his terror of germs and contamination. His condition costs him his job as a prominent homicide detective in the San Francisco Police Department, but he continues to solve crimes with the help of his assistant and his former boss.
- Starring: Tony Shalhoub, Ted Levine, Traylor Howard, Jason Gray-Stanford, Bitty Schram
- TV Network: USA
- Premiere Date: Jul 12, 2002
- Genre: Crime
- Executive producers: Andy Breckman, David Hoberman