The show opens with Bob Odenkirk and David Cross hosting "The Mr. Show Water Cooler," a parody of Politically Incorrect described as a "political jam session -- featuring absolutely no experts." The guest panelists are Xona (Becky Thyres), a porn star, and Keith (Jay Johnston), a skydiver. It takes a while for Bob and David to think of a topic, then David mentions that he heard a comedian say that a senator was planning to have plastic surgery "to remove the NRA's lips from his ass." He and Bob start to discuss this as though it was an actual news event, until Keith interrupts them, to point out that it was just a joke. Keith is forced to spend the remainder of the show in the "Smarty Pants," a giant pair of pants filled with vanilla custard. From there, he watches the International News Report with anchor Aviana Prujmpur (Jill Talley), who reports on a monsoon in Myanmar, the devaluing of yen, and a major event in the U.S. -- "the president has allegedly farted." This last story is causing a national uproar, and there's even a clip of Chris Rock talking about it on his HBO show. President Fruitty (Johnston) eventually addresses the nation, stating, "This matter should be between me, my wife, my pants, and our God." God (Bob Odenkirk) Himself appears in another sketch. He's a smooth-talking, club-hopping, show-biz type, and He records a book-on-tape of His autobiography, "My Life in the Fast Lane." Later, the reality show, "Probings," is dedicated to the topic, "Monster Parties -- Fact or Fiction." As the narrator solemnly intones, "Dracula...The Wolfman...The Mummy...Would these monsters ever assemble as a group in a party setting, to dance or eat and drink together? While skeptics declare it impossible, novelty songs seem to suggest quite the opposite."