Seth MacFarlane Captain Ed Mercer Actor, Executive Producer Adrianne Palicki Commander Kelly Grayson Actor Penny Johnson Dr. Claire Finn Actor Scott Grimes Lieutenant Gordon Malloy Actor Peter Macon Lieutenant Commander Bortus Actor Halston Sage Chief Security Officer Alara Kitan Actor J. Lee Lieutenant John Lamarr Actor Mark Jackson Isaac Actor Chad L. Coleman Klyden Actor Jessica Szohr Lieutenant Talla Keyali Actor Jason Alexander Olix Guest Star Mike Henry Dann Guest Star Leighton Meester Laura Guest Star Kelly Hu Admiral Ozawa Guest Star Michaela McManus Lt. Janel Gillis Guest Star Chris Johnson Cassius Guest Star Will Sasso Mooska Guest Star Kai Wener Ty Finn Guest Star Brian Tanner Marcus Finn Guest Star Brannon Braga Executive Producer David A. Goodman Executive Producer Jason Clark Executive Producer Liz Heldens Executive Producer