David Kohan Creator, Executive Producer, Writer Max Mutchnick Creator, Executive Producer, Writer Eric McCormack Will Truman Actor Debra Messing Grace Adler Actor Sean Hayes Jack McFarland Actor Megan Mullally Karen Walker Actor Shelley Morrison Rosario Salazar Guest Star Gregory Hines Ben Doucette Guest Star Sydney Pollack George Truman Guest Star Corey Parker Josh Guest Star Tom Gallop Rob Guest Star Leigh-Allyn Baker Ellen Guest Star Mimi Cozzens BJ Guest Star Lou Cutell Mr. Arthur Pressman Guest Star Aaron Lustig Marv Guest Star Mary Pat Gleason Sally Guest Star Ralph Drischell Mr. Munitz Guest Star Lindsey Fields Nurse 1 Guest Star Jo Marie Payton Mrs. Freeman Guest Star Marshall Manesh Mr. Zamir Guest Star Lyn Alicia Henderson Nurse Guest Star Amy Crofoot Secretary Guest Star James Burrows Director, Executive Producer Jon Kinnally Writer Alex Herschlag Writer Jhoni Marchinko Writer Jeff Greenstein Writer Adam Barr Writer Katie Palmer Writer Michelle Bochner Spitz Writer Ellen Idelson Writer Gail Lerner Writer Tim Kaiser Producer Tracy Poust Writer Laura Kightlinger Writer