Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Nelsan Ellis Shinwell Johnson Actor Jordan Gelber M.E. Hawes Guest Star Dan Lauria Louis Garmendia Guest Star Rebecca Luker Virginia Spivey Guest Star Paul O'Brien Paul Fontino Guest Star Carson Elrod Rueben Drexel Guest Star Marcus Choi Marco Guest Star David Corenswet Houston Spivey Guest Star Ben Biggers Josh Guest Star Zainab Jah Vicki Guest Star Charlbi Dean Kriek Beautiful Woman Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Kelly Wheeler Writer Michael Hekmat Director