Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Bebe Neuwirth Dr. Lilith Sternin Guest Star Ashley Thomas Alice May Doyle Guest Star Millicent Martin Gertrude Moon Guest Star Brent Spiner Albert Guest Star Kevin Chamberlin Guy in Waiting Room Guest Star James Oliver James Guest Star Laurel Green Flight Attendant Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Sheldon Epps Director Lori Kirkland Baker Writer