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Season 22 – Grey's Anatomy

Play trailer Poster for Season 22 – Grey's Anatomy Oct 2025 Drama Play Trailer Watchlist
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This high-intensity medical drama follows a team of doctors at Grey Sloan Memorial Hospital who are faced with life-or death decisions on a daily basis. They seek comfort from one another, and, at times, more than just friendship. Together they discover that neither medicine nor relationships can be defined in black and white.
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Grey's Anatomy — Season 22

Audience Reviews

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Dionne C @DioNN Jun 8 Honestly, this should have ended 10 seasons ago. See more Leslie O. @RT64307070 May 9 Please don’t get rid of Harry Shrum Jr. Please. He’s no Izzy Steven’s See more Sierra B @sbmbolin Apr 19 I've always loved Grey's but I believe it is time to wrap it up! See more Chantal G @thepuce27 Jan 11 I still really like the series, but you can tell it's losing steam a bit. See more Lillan S @Lillan Nov 21 Still love Grey’s but sometimes the catastrophes get a bit too much and feel like the previous disasters… See more Stephen C @bob25009 Oct 16 4 successful American Broadcasting Company episodes. See more Read all reviews
Grey's Anatomy — Season 22

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Cast & Crew

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Shonda Rhimes

Creator

Ellen Pompeo

Dr. Meredith Grey

Chandra Wilson

Dr. Miranda Bailey

James Pickens Jr.

Dr. Richard Webber

Kevin McKidd

Owen Hunt

Caterina Scorsone

Amelia Shepherd

Episodes

Episode 1 Aired Oct 9, 2025 Only the Strong Survive After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own; confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation. Details Episode 2 Aired Oct 16, 2025 We Built This City The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations; Meredith spends time with Amelia. Details Episode 3 Aired Oct 23, 2025 Between Two Lungs A high-risk lung transplant pushes the surgical team to their limits; Bailey juggles a trauma patient whose treatment hangs in the balance. Details Episode 4 Aired Oct 30, 2025 Goodbye Horses The interns juggle a bizarre trauma; a complex breast reconstruction forces Meredith into a tense partnership. Details Episode 5 Aired Nov 6, 2025 Sometimes I Feel Like a Motherless Child Jo navigates a challenging case with a pregnant mother; Blue and Jules care for a diabetic patient; Simone treats a patient with a surprising revelation. Details Episode 6 Aired Nov 13, 2025 When I Crash Grey Sloan takes in patients following a catastrophic bus accident; Teddy and Owen have an awkward encounter; Richard tests Bailey's patience. Details Episode 7 Aired Jan 8, 2026 Skyfall Winston and Ben fight to save Jo's life; Teddy supports Link; Owen and Jules battle to save a young man; Lucas forms an unexpected bond with a patient. Details Episode 8 Aired Jan 15, 2026 Heavy on Me Bailey and Owen join forces to save a tumor patient; Richard faces an internal battle; Jules struggles with her feelings for Winston. Details Episode 9 Aired Jan 22, 2026 Fortunate Son Richard continues to navigate his health; Meredith and Nick are visited by Nick's estranged sister from Boston. Details Episode 10 Aired Jan 29, 2026 Strip That Down Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition; Bailey joins Owen and Blue on a paramedic ride-along. Details Episode 11 Aired Feb 26, 2026 (If You Want It) Do It Yourself Teddy and Winston clash over a case; Owen and Jules treat a urologist; Lucas struggles with prioritizing patients. Details Episode 12 Aired Mar 5, 2026 Get Lucky Tensions rise as Teddy and Winston take on a complex procedure; Kavita and Ben try to impress the new plastics attending; Jo and Link leave the babies with a nanny for the first time. Details Episode 13 Aired Mar 12, 2026 Love the Way You Lie Richard tackles a shocking case on his first day back; Kavita and Jules prepare for a high-stakes presentation; Bailey must have a difficult conversation with a beloved patient; Jo works to baby-proof the loft. Details Episode 14 Aired Mar 19, 2026 Wrecking Ball A couple land in the hospital with life-altering injuries after a wrecking ball destroys their home; Lucas and Simone struggle to support a young, terminally ill patient; Richard hosts a prostate screening event. Details Episode 15 Aired Mar 26, 2026 Take Me to the River Bailey and Blue are forced to confront the emotional costs of experimental care; Owen, Teddy, Simone and Dani help out at a busy rural hospital; Richard attempts to spread information about early prostate screenings to the community. Details Episode 16 Aired Apr 2, 2026 Feel It Still Jo returns for her first full day back from leave; Owen struggles to keep it together when someone close to him is admitted to Grey Sloan; Bailey navigates hospital leadership. Details Episode 17 Aired Apr 30, 2026 Through the Fire A Station 19 firefighter lands in the emergency room for severe burn treatment; the team treats an elderly patient impaled by an art structure. Details Episode 18 Aired May 7, 2026 Bridge Over Troubled Water After a catastrophic bridge collapse sends dozens of victims to Grey Sloan, the hospital activates its full disaster response as they race to treat a surge of critically injured patients. Details

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Grey's Anatomy — Season 22

Grey's Anatomy View more photos

Season Info

Director
Rob Corn, Kevin McKidd, Debbie Allen, Chandra Wilson, Allison Liddi-Brown, Jeannot Szwarc
Creator
Shonda Rhimes
Executive Producer
Betsy Beers, Zoanne Clack, Andy Reaser, Meg Marinis
Screenwriter
Julie Wong, Jess Righthand, Jase Miles-Perez
Network
ABC
Rating
TV-14 (L|S)
Genre
Drama
Original Language
English
Release Date
Oct 9, 2025
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