Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Tim Matheson Dr. Brick Breeland Actor, Director Kaitlyn Black AnnaBeth Nass Actor Laura Bell Bundy Shelby Sinclair Guest Star Ross Philips Tom Long Guest Star Mallory Moye Wanda Long Guest Star Brandi Burkhardt Crickett Watts Guest Star Reginald VelJohnson Dash DeWitt Guest Star Steven M. Porter Frank Moth Guest Star Matt Hobby Rudy Truitt Guest Star Bill Parks Chicken Truitt Guest Star Aynsley Bubbico Sadie Guest Star Kevin Sheridan Rockett Truitt Guest Star Matt Lowe Meatball Guest Star Carla Renata Susie Guest Star John Marshall Jones Wally Maynard Guest Star Leila Gerstein Executive Producer, Writer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer David Paymer Director Michael Schultz Director Les Butler Director Richard W. Abramitis Director Mary Lou Belli Director Bethany Rooney Director Brandi Bradburn Director April Blair Writer Tamar Laddy Writer Kendall Sand Writer Adam Milch Writer Amy Roy Writer Ari Posner Writer