The quints are full-blown threenagers now, and Danielle and Adam must figure out how to make them more disciplined; Adam tries to balance working from home, but after Ava gets sick, the Busbys make a shocking discovery in their house.

The quints have their first sleepover at the Mills when the Busbys are forced to leave their home for a few days; fearing for the girls' health after prolonged exposure to mold, Danielle and Adam bring them to the doctor.

Thanksgiving is right around the corner, but celebrating is the last thing on the Busbys' minds; tensions run high between Adam and Danielle as they continue the hunt for a new house and the quints undergo their first school testing.

The Busbys move out of their mold-infested home, but transitioning isn't easy; the quints night time antics escalate until Adam and Danielle split up their bedrooms for the first time; Adam plans a surprise birthday party for Danielle.

As the Busbys navigate life in their new home, Adam and Danielle try to salvage what's left of the Christmas season; when Danielle learns she needs surgery on her wisdom teeth, Adam struggles to keep the house afloat and deliver a perfect Christmas.

Adam gets a great work opportunity, but he needs to rely on the chaotic quints to make it a success; when Parker's anxiety gets the best of her, the Busbys must look for solutions; Blayke follows in her mom's footsteps with a new hobby.

It's a dream come true for the Busby girls as the whole family goes on a Disney cruise; Adam gets a huge job offer that means major changes for the family, causing tension between him and Danielle.

A trip to the Busbys' old home brings a surprise; Adam's job situation faces a new development; Hazel goes to her eye appointment; Danielle and the Quints come up with a creative way to give back to the NICU.