Splice (2010)



Critic Consensus: It doesn't take its terrific premise quite as far as it should, but Splice is a smart, well-acted treat for horror fans.

Movie Info

Superstar genetic engineers Clive and Elsa specialize in splicing DNA from different animals to create incredible hybrids. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But, when the company that funds their research forbids it, Clive and Elsa secretly take their boldest experimentation underground -- risking their careers by pushing the boundaries of science to serve their own curiosity and ambition. The result is Dren, an amazing, strangely beautiful … More

Rating: R (for disturbing elements including strong sexuality, nudity, sci-fi violence and language)
Genre: Science Fiction & Fantasy, Horror
Directed By:
Written By: Antoinette Terry Bryant, Vincenzo Natali, Doug Taylor
In Theaters:
On DVD: Oct 5, 2010
Box Office: $17.0M
Warner Brothers - Official Site


as Clive Nicoli

as Elsa Kast

as William Barlow

as Gavin Nicoli

as Joan Chorot

as Child Dren
Show More Cast

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Critic Reviews for Splice

All Critics (184) | Top Critics (38)

While it appears to be a pretty straightforward story, the actual film gives you more in scares and chills - and more to think about - than you'd expect.

Full Review… | January 18, 2014
7M Pictures

Who would have thought talent of that calibre would combine to create such a catastrophic stinker.

Full Review… | February 15, 2013
Georgia Straight

Because of the writers' choice to stay so superficial, we get a sluggishly-paced, forgettable thriller.

Full Review… | October 1, 2012

It's the very special genetic engineering episode of Parenthood that was too hot for TV.

Full Review… | April 4, 2011

Splice ends up being disturbing, but not particularly affecting. The use of the human characters is too uneven to pull off the desired effect.

Full Review… | March 30, 2011

"Splice" is one of those movies that just makes you ache, because it almost achieves greatness.

Full Review… | October 13, 2010

Audience Reviews for Splice

Entertaining albeit stupid genetic experiment thriller that can't decide how it wants to make the audience feel about its creature. The somewhat lousy special effects do not exactly help creating a connection to the "monster". Another problem are the characters that range from idiotic, flat to downright unlikable. So overall everything that happens makes you feel entirely indifferent.

Jens S.

Super Reviewer


A pair of genetic biologists succeed in splicing the DNA of various creatures with that of a human being and the resulting life form begins to take over their lives as they try to hide their secret experiment. Splice is very much in the old "mad scientists play God and reap the consequences" school of horror stories, giving the Frankenstein formula a modern sci-fi spin. In fact the story interestingly stays away from the man makes monster idea for the early stages, preferring David Cronenberg style psychological horror, particularly during the rather disturbing Mommie Dearest sequence and when the bizarre sexual ambiguity of their creation becomes apparent. Disappointingly it soon settles back into the usual creature feature for an overly predictable finale which is a shame because it was actually starting to explore some interesting ideas. The production design is a little suspect (baby Dren looks suspiciously like an oven ready chicken with a rabbit's head) but Brody and Polley are as watchable as always and it's weird enough to maintain the attention for the duration, but it's nowhere near as inventive as Prometheus which covered a lot of the same ground.

xGary Xx

Super Reviewer

I enjoyed the idea of the story. It certainly does present problems that exist with genetic research. Although the details leave a bit to be desired. The business that a stick through the heart does not kill you, but a rock smashed on your head does is fancy writing. But never might its shortfalls, watch the movie.

Red Lats

Super Reviewer

Splice Quotes

– Submitted by Chris P (4 years ago)
– Submitted by Chris P (4 years ago)

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