Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Brooke Smith Dr. Erica Hahn Actor Amy Aquino Guest Star Larry Brandenburg Guest Star Bre Blair Guest Star John Sloan Guest Star Steven W. Bailey Guest Star Kathleen Early Guest Star Max Burkholder Guest Star Carol Ann Susi Guest Star Candice Afia Guest Star Amrapali Ambegaokar Guest Star Tymberlee Hill Guest Star Gloria Garayua Guest Star Molly Kidder Guest Star Mark Saul Guest Star Winston Story Guest Star Joseph Williamson Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Debora Cahn Writer Eric Stoltz Director