Harry, Jason, Sherman and Kelly all went to high school together; several years out from graduation, their lives aren't exactly what they'd had in mind. Sherman is a diet guru who recently hijacked a pastry truck after finding out his wife left him; financial expert Jason is facing indictment and is on the verge of suicide; and unhappily divorced Harry discovers former valedictorian Kelly working as a questionable "masseuse." A series of emergencies will bring this group back together -- and with the help of Dr. Joanna Lupone, they'll be able to overcome anything. Hopefully.