Walt Becker Director Jason Lee Dave Seville Actor Tony Hale Scruggs Actor Kimberly Williams-Paisley Samantha Actor Josh Green Miles Actor Bella Thorne Ashley Actor Justin Long Alvin Voice Matthew Gray Gubler Simon Voice Jesse McCartney Theodore Voice Kaley Cuoco Eleanor Voice Anna Faris Jeanette Voice Christina Applegate Brittany Voice John Waters First Class Passenger Actor Stefan Gordy DJ at Party Actor Jennifer Coolidge Ms. Price Actor Uzo Aduba TSA Officer Actor Randi Mayem Singer Screenwriter Adam Sztykiel Screenwriter Janice Karman Producer Ross Bagdasarian Jr. Producer Karen Rosenfelt Executive Producer Arnon Milchan Executive Producer John H. Starke Executive Producer Steve Waterman Executive Producer Peter Collister Cinematographer Ryan Folsey Film Editing Mark Mothersbaugh Original Music Richard Holland Production Design Paul D. Kelly Supervising Art Direction Frank Galline Set Decoration Mary Claire Hannan Costume Design Sheila Jaffe Casting Jackie Burch Casting