Richard Kelly Director, Screenwriter Jake Gyllenhaal Donnie Darko Actor Jena Malone Gretchen Ross Actor Drew Barrymore Ms. Karen Pomeroy Actor James Duval Frank Actor Maggie Gyllenhaal Elizabeth Darko Actor Mary McDonnell Rose Darko Actor Holmes Osborne Eddie Darko Actor Katharine Ross Dr. Lilian Thurman Actor Patrick Swayze Jim Cunningham Actor Noah Wyle Dr. Monnitoff Actor Daveigh Chase Samantha Darko Actor Arthur Taxier Dr. Fisher Actor Stuart Stone Ronald Fisher Actor Alex Greenwald Seth Devlin Actor Joan Blair Mystery Woman Actor Fran Kranz Passenger Actor David St. James Bob Garland Actor Rachel Winfree Shanda Riesman Actor Sean McKittrick Producer Nancy Juvonen Producer Hunt Lowry Executive Producer Casey La Scala Executive Producer Steven Poster Cinematographer Alec Hammond Production Design April Ferry Costume Design Eric Strand Film Editing Sam Bauer Film Editing Michael Andrews Original Music