Jim Abrahams Director, Producer, Executive Producer Meryl Streep Lori Reimuller Actor, Executive Producer Fred Ward Dave Reimuller Actor Seth Adkins Robbie Reimuller Actor Margo Martindale Marjean Actor Allison Janney Dr. Melanie Abbasac Actor Oni Faida Lampley Marsha Williams Actor Leo Burmester Bob Purdue Actor Tom Butler Jim Peterson Actor Mairon Bennett Lynne Reimuller Actor Michael Yarmush Mark Reimuller Actor Sean McCann Actor Millicent Kelly Self Philip Williams Actor Philip Akin Actor Damir Andrei Actor Marcia Bennett Gail Actor Charlie Abrahams Playroom Playmate (uncredited) Actor Lorraine Brockway Lili's Grandmother Actor Douglas Foster Orderly Actor Mark Taylor Spinal Tap Physician Actor Ann Beckett Screenwriter Michael Jaffe Executive Producer Howard Braunstein Executive Producer Pierre Letarte Cinematographer Terry Stokes Film Editing Hummie Mann Original Music Karen Bromley Production Design Wayne Jacques Set Decoration Lynne MacKay Costume Design Deirdre Bowen Casting Jackie Burch Casting