Treat Williams Dr. Andrew Brown Actor Gregory Smith Ephram Brown Actor Emily VanCamp Amy Abbott Actor Debra Mooney Edna Abbott Actor John Beasley Irv Harper Actor Vivien Cardone Delia Brown Actor Chris Pratt Bright Abbott Actor Stephanie Niznik Nina Feeney Actor Merrilyn Gann Rose Abbott Actor Tom Amandes Dr. Harold Abbott Actor Scott Wolf Dr. Jake Hartman Actor Sarah Drew Hannah Rogers Actor Justin Baldoni Guest Star Steven R McQueen Guest Star Charles Durning Guest Star Leslie Hope Guest Star Jayne Brook Guest Star Christopher Egan Guest Star Reggie Austin Guest Star Renee Taylor Guest Star Greg Berlanti Executive Producer, Writer Mickey Liddell Executive Producer Nancy Won Writer Tom Garrigus Writer Perry Lang Director David Hudgins Writer Josh Reims Writer Rina Mimoun Writer Barbie Kligman Writer Bryan M. Holdman Writer Arvin Brown Director Anna Fricke Writer Peter Markle Director Joyce Chopra Director Joe Pennella Director David Paymer Director Michael Pavone Director Ellen S. Pressman Director David Petrarca Director