George Clooney Director, Screenwriter, Producer Matt Damon Gardner Actor Julianne Moore Margaret, Rose Actor Oscar Isaac Roger Actor Glenn Fleshler Ira Actor Alex Hassell Louis Actor Marah Fairclough Shopping Woman Actor Megan Ferguson June Actor Noah Jupe Nicky Actor Michael D. Cohen Stretch Actor Jack Conley Hightower Actor Diane Dehn Virginia Actor Tim Neff Protestor No. 4 Actor Gary Basaraba Uncle Mitch Actor Emily Goss Clinic Mom Actor Karimah Westbrook Mrs. Mayers Actor Tony Espinosa Andy Actor Leith M. Burke Mr. Mayers Actor Joel Coen Screenwriter Ethan Coen Screenwriter Grant Heslov Screenwriter, Producer Teddy Schwarzman Producer Ethan Erwin Executive Producer Barbara A. Hall Executive Producer Joel Silver Executive Producer Daniel Steinman Executive Producer Hal Sadoff Executive Producer Robert Elswit Cinematographer Stephen Mirrione Film Editing Alexandre Desplat Original Music Jim Bissell Production Design Jenny Eagan Costume Design Ellen Chenoweth Casting