Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Shane West Actor Scott Grimes Dr. Archie Morris Actor Laura Innes Dr. Kerry Weaver Actor John Stamos Dr. Tony Gates Actor Dominic Janes Alex Taggart Guest Star Michelle Hurd Courtney Brown Guest Star J.P. Manoux Dr. Dustin Crenshaw Guest Star Forest Whitaker Curtis Ames Guest Star Brian Lester Brian Lester Guest Star Sara Gilbert Jane Figler Guest Star Richard Kuhlman Guest Star Malaya Drew Rivera Katey Alvaro Guest Star Cassi Thomson Lulu Davis Guest Star Deezer D Nurse Malik McGrath Guest Star Paula Malcomson Meg Riley Guest Star Remy Thorne Milo Guest Star Emily Wagner Doris Pickman Guest Star Sarah Benoit Melanie Guest Star Vyto Ruginis Wright Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer