Martin Sheen President Josiah "Jed" Bartlet Actor Bradley Whitford Dep. Chief of Staff Josh Lyman Actor John Spencer Chief of Staff Leo McGarry Actor Richard Schiff Communications Dir. Toby Ziegler Actor Allison Janney Press Secretary Claudia Jean "C.J." Cregg Actor Dulé Hill Charlie Young Actor Janel Moloney Donna Moss Actor Stockard Channing Abigail "Abbey" Bartlet Actor Gary Cole Vice President Bob Russell Guest Star Terry O'Quinn General Nicholas Alexander Guest Star Anna Deavere Smith Nancy McNally Guest Star Jay Mohr Taylor Reid Guest Star Ryan Cutrona CIA Director George Rollie Guest Star Steve Ryan Secretary of Defense Miles Hutchinson Guest Star Armin Mueller-Stahl Israeli Prime Minister Efraim "Eli" Zahavy Guest Star Joshua Malina Will Bailey Guest Star Thomas Kopache Assistant Secretary of State Bob Slatterly Guest Star Renee Estevez Nancy Guest Star John Wells Executive Producer