This film's story is one of the best constructed I have seen in the genre (sci-fi/horror). The lab is very credible, the biology not too far off except maybe impossible, and the psychology completely understandable. I think the film went very far and made the spliced girl a bit too monstrous in the end. Maybe they had to for an horror film, but maybe there is a more terrible ending that does not make the monster a killer. Then again, they tried to kill the monster first, so it is monsters against monster in this case. Very good progression and I give it a 5 stars until when Dren change sex.