Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Essence Atkins Captain Greta Cooper Guest Star Anne Dudek Dr. Amber Volakis Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Peter Jacobson Dr. Chris Taub Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Heather Fox Dr. Ashka Guest Star Jonathan Sadowski Dr. Mason Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Jason Manuel Olazabal Dr. O'Reilly Guest Star Andy Comeau Dr. Travis Brennan Guest Star Meera Simhan Dr. Jody Desai Guest Star Melinda Dahl Twin 1 Guest Star Caitlin Dahl Twin 2 Guest Star Kathryn Adams Number 23 Guest Star Larkin Campbell Dave Guest Star Jaimarie Bjorge Beautiful Doctor Guest Star Bobbin Bergstrom Nurse Guest Star Carmen Argenziano Henry Dobson Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer