It's tone and the environment of it seems a bit off track some time and it's not that because of some funny sequences, it's just the surrounding of it and the characters they just aren't palpable to it. 50/50 may come off a bit eerie and not easy to digest but it's advantage is that it floats on a light mode and delivers everything in appropriate amount. Jonathan Levine's execution seems like a TV dramatic episode along with the writer Will Reiser. Joseph Gordon-Levitt is doing some of the best work of his career in here and along with the help of a good supporting cast like Anna Kendrick, Bryce Dallas Howard and Seth Rogen it pretty much gets it right on performance level. 50/50 even though being of around 100 minutes seems a bit long, slow and quite pretentious and one of the main thing it lacks is carrying out the emotional or intense sequences to the audience.