Lana Wachowski Director, Screenwriter, Producer Lilly Wachowski Director, Screenwriter, Producer Tom Tykwer Director, Screenwriter, Producer, Original Music Tom Hanks Zachry Actor Halle Berry Luisa Rey Actor Jim Broadbent Timothy Cavendish Actor Hugo Weaving Nurse Noakes Actor Jim Sturgess Adam Ewing Actor Bae Doo-na Sonmi-451 Actor Ben Whishaw Robert Frobischer Actor James D'Arcy Rufus Sixsmith Actor Susan Sarandon Madame Horrox Actor Hugh Grant Kona Chief Actor Keith David Joe Napier Actor Xun Zhou Yoona-939 Actor David Gyasi Autua Actor Robert Fyfe Old Salty Dog Actor Martin Wuttke Mr. Boerhaave Actor Robin Morrissey Young Cavendish Actor Brody Nicholas Lee Javier Gomez Actor Grant Hill Producer Stefan Arndt Producer Philip Lee Executive Producer Uwe Schott Executive Producer Wilson Qiu Executive Producer John Toll Cinematographer Frank Griebe Cinematographer Uli Hanisch Production Design Hugh Bateup Production Design Alexander Berner Film Editing Johnny Klimek Original Music Reinhold Heil Original Music Kym Barrett Costume Design Pierre-Yves Gayraud Costume Design Stephan O. Gessler Supervising Art Direction Kai Koch Supervising Art Direction Charlie Revai Supervising Art Direction Rebecca Alleway Set Decoration Peter Walpole Set Decoration Lora Kennedy Casting Lucinda Syson Casting Gigi Oeri Associate Producer