Terry Gilliam Director, Screenwriter Johnny Depp 'Uncle' Raoul Duke Actor Benicio del Toro Oscar Zeta Acosta ("Dr. Gonzo") Actor Craig Bierko Lacerda Actor Ellen Barkin Waitress at North Star Cafe Actor Gary Busey Highway Patrolman Actor Cameron Diaz Blonde TV Reporter Actor Flea Musician in Matrix Club Men's Room Actor Mark Harmon Magazine Reporter at Mint 400 Actor Katherine Helmond Desk Clerk at Mint Hotel Actor Michael Jeter L. Ron Bumquist Actor Penn Jillette Barker at Bazooko Actor Lyle Lovett Road Person Actor Tobey Maguire Hitchhiker Actor Christina Ricci Lucy Actor Harry Dean Stanton Judge Actor Tim Thomerson Hoodlum Actor Hunter S. Thompson Writer Tony Grisoni Screenwriter Tod Davies Screenwriter Alex Cox Screenwriter Harold Bronson Executive Producer Patrick Cassavetti Producer Richard Foos Executive Producer John Jergens Associate Producer Laila Nabulsi Producer Stephen Nemeth Producer Elliot Rosenblatt Co-Producer Ray Cooper Original Music Michael Kamen Original Music Nicola Pecorini Cinematographer Lesley Walker Film Editing Margery Simkin Casting Alex McDowell Production Design Chris Gorak Art Director