Tom Kapinos Creator, Executive Producer David Duchovny Hank Moody Actor, Executive Producer Natascha McElhone Karen Actor Madeleine Martin Becca Moody Actor Madeline Zima Mia Lewis Actor Evan Handler Charlie Runkle Actor Pamela Adlon Marcy Runkle Actor Meagan Good Guest Star Jason Beghe Guest Star Stephen Tobolowsky Guest Star Scott Michael Foster Guest Star Camilla Luddington Guest Star Vanessa Angel Guest Star Peter Berg Guest Star RZA Guest Star Jim Calloway Guest Star Fatso Fasano Guest Star Sara Targum Guest Star Maia Tarin Guest Star Jim Tavaré Guest Star Kinetic Guest Star Ervin Ross Guest Star