Tom Kapinos Creator, Executive Producer David Duchovny Hank Moody Actor, Executive Producer Natascha McElhone Karen Actor Madeleine Martin Becca Moody Actor Evan Handler Charlie Runkle Actor Pamela Adlon Marcy Runkle Actor Michael Imperioli Guest Star Brandon T. Jackson Guest Star Stephen Tobolowsky Guest Star Oliver Cooper Guest Star Mary Lynn Rajskub Guest Star Mercedes Mason Guest Star Brigette Davidovici Guest Star Chris Titone Guest Star John Madison Tye Guest Star Heather Graham Guest Star DJ Lubel Guest Star Alonzo Bodden Guest Star Darrell Britt-Gibson Guest Star Jade Catta-Preta Guest Star Jim Florentine Guest Star Dean Wayne Guest Star