Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Ophelia Lovibond Kitty Winter Guest Star Ato Essandoh Alfredo Llamosa Guest Star Jordan Gelber M.E. Hawes Guest Star Lawrence Gilliard Jr. Dwyer Kirk Guest Star Dakin Matthews James Connaughton Guest Star Brian Lee Huynh Brett Won Guest Star Luke Robertson Louis Carlisle Guest Star Julienne Hanzelka Kim Shauna Milius Guest Star Robert Capron Mason Guest Star Andrea Syglowski Sarah Jacoby Guest Star Carra Patterson Jessa Guest Star Seiko Suzuki Shih Akiko Guest Star Catrina Ganey Maid Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer Craig Sweeny Executive Producer, Writer Larry Teng Director