Michael Sheen William Masters Actor, Producer Lizzy Caplan Virginia Johnson Actor Caitlin FitzGerald Libby Masters Actor Teddy Sears Dr. Austin Langham Actor Annaleigh Ashford Betty DiMello Actor Mather Zickel Guest Star Necar Zadegan Guest Star Kevin Christy Guest Star Waleed Zuaiter Guest Star Maggie Grace Guest Star Jack Laufer Guest Star JB Blanc Guest Star Isabelle Fuhrman Guest Star Christopher Grove Guest Star Jim Ortlieb Guest Star Leo Marks Guest Star Michelle Ashford Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Judith Verno Executive Producer Amy Lippman Executive Producer, Writer Dean Parisot Director