Dylan Walsh Dr. Sean McNamara Actor Julian McMahon Dr. Christian Troy Actor John Hensley Matt McNamara Actor Joely Richardson Julia McNamara Actor Valerie Cruz Grace Santiago Actor Jessalyn Gilsig Gina Russo Guest Star Don McManus David Collins Guest Star Phillip Rhys Chaudhary Jude Sawyer Guest Star Brenda Strong Iris Guest Star George Wyner Doctor Guest Star Vincent Angell Kurt Dempsey Guest Star Gabrielle Carteris Ellie Collins Guest Star John Marshall Jones Victor Guest Star Saemi Nakamura Leigh Moriata Guest Star James Patrick Stuart Serge Guest Star Valerie Wildman Shelly Edwards Guest Star Roma Maffia Dr. Liz Cruz Guest Star Linda Klein Nurse Linda Guest Star Kristen Williams Jasmine Guest Star