Timothy Dalton Sir Malcolm Murray Actor Eva Green Vanessa Ives Actor Josh Hartnett Ethan Chandler Actor Reeve Carney Dorian Gray Actor Billie Piper Brona Croft Actor Danny Sapani Sembene Actor Harry Treadaway Dr. Victor Frankenstein Actor Rory Kinnear The Creature Actor Patti LuPone Dr. Seward Actor Wes Studi Kaetenay Actor Shazad Latif Dr. Henry Jekyll Actor John Logan Writer, Executive Producer Sam Mendes Executive Producer Paco Cabezas Director