America Ferrera Betty Suarez Actor Eric Mabius Daniel Meade Actor Tony Plana Ignacio Suarez Actor Ana Ortiz Hilda Suarez Actor Judith Light Claire Meade Actor Christopher Gorham Henry Grubstick Actor Ashley Jensen Christina McKinney Actor Becki Newton Amanda Tanen Actor Michael Urie Marc St. James Actor Mark Indelicato Justin Suarez Actor Rebecca Romijn Alexis Meade Actor Vanessa Williams Wilhelmina Slater Actor Freddy Rodríguez Gio Rossi Guest Star Gene Simmons Himself Guest Star Alec Mapa Suzuki St. Pierre Guest Star Larry King Himself Guest Star Eddie Cibrian Coach Diaz Guest Star Jasmine Anthony Antonella Guest Star Bernard Addison Principal Hayward Guest Star Elijah DeJesus Little Betty Guest Star Giancarlo Rodriguez Little Gio Guest Star Cody Klop Little Daniel Guest Star Macall Manor Little Amanda Guest Star David Johnson Teacher Guest Star Silvio Horta Executive Producer Ben Silverman Executive Producer Salma Hayek Executive Producer Jose Tamez Executive Producer Brian Tanen Writer Wendey Stanzler Director