Etan Cohen Director, Screenwriter Will Ferrell Sherlock Holmes Actor, Producer John C. Reilly Dr. Watson Actor Rebecca Hall Grace Hart Actor Rob Brydon Inspector Lestrade Actor Steve Coogan Gustav Klinger Actor Kelly Macdonald Mrs. Martha Hudson Actor Hugh Laurie Mycroft Actor Lauren Lapkus Millicent Actor Pam Ferris Queen Victoria Actor Ralph Fiennes Professor James Moriarty Actor Chris Henchy Executive Producer Jessica Elbaum Executive Producer M. Riley Executive Producer David Mimran Executive Producer Jordan Schur Executive Producer Adam McKay Producer Jimmy Miller Producer Clayton Townsend Producer Oliver Wood Cinematographer Dean Zimmerman Film Editing Erik Jessen Film Editing Mark Mothersbaugh Original Music Sauryansh Singh Original Music James Hambidge Production Design Beatrix Aruna Pasztor Costume Design Lucinda Syson Casting