Patrick Wilson Dr. Michael Holt Actor Jennifer Ehle Anna Paul Actor Margo Martindale Rita Perkins-Hall Actor Pablo Schreiber Anton Little Creek Actor Rachelle Lefevre Dr. Kate Sykora Actor Rhys Coiro Dr. Zeke Barnes Guest Star Gbenga Akinnagbe Dr. Leo "Bax" Baxter Guest Star Armando Riesco Tavo Guest Star Raúl Esparza Phillip Romero Guest Star Mike Doyle Victor Lantz Guest Star Sue Jean Kim Nurse Colette Guest Star Cara Buono Carol Gordan Guest Star Chris Jackson Rafael Douglas Guest Star Amina Robinson Lisa Douglas Guest Star Tyler Silva Nathan Douglas Guest Star Aaron Lazar Steve Powers Guest Star Tijuana Ricks Nurse Charisse Guest Star John Windsor-Cunningham Wealthy Man Guest Star Jeannine Moore Wealthy Woman Guest Star Brian Delate Traffic Cop Guest Star Aaron Bantum Paolo Guest Star Brynn O'Malley Liz Martin Guest Star Susannah Grant Executive Producer Jonathan Demme Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Neal Baer Executive Producer Jonathan Greene Writer Peter Werner Director