Zachary Quinto Dr. Oliver Thredson Actor Joseph Fiennes Monsignor Timothy Howard Actor Sarah Paulson Lana Winters Actor Evan Peters Kit Walker Actor Lily Rabe Sister Mary Eunice Actor Lizzie Brocheré Grace Actor James Cromwell Dr. Arthur Arden Actor Jessica Lange Sister Jude Actor Chloë Sevigny Shelley Guest Star Adam Levine Leo Morrison Guest Star Jenna Dewan Teresa Morrison Guest Star Clea Duvall Wendy Peyser Guest Star Fredric Lehne Frank McCann Guest Star Devon Graye Jed Potter Guest Star Robin Weigert Cynthia Potter Guest Star John Aylward Father Malachi Guest Star Andrew Rothenberg Mr. Potter Guest Star Jenny Wade Prostitute Guest Star Jennifer Holloway Barb Guest Star Vanessa Mizzone Lois Guest Star Naomi Grossman Pepper Guest Star Gloria Laino The Mexican Guest Star Casey Wyman Daniel Guest Star Henry Watkins Walter Guest Star Chelsey Valentine Little Girl In Blue Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Dante Di Loreto Executive Producer Tim Minear Executive Producer