Zachary Quinto Dr. Oliver Thredson Actor Joseph Fiennes Monsignor Timothy Howard Actor Sarah Paulson Lana Winters Actor Evan Peters Kit Walker Actor Lily Rabe Sister Mary Eunice Actor Lizzie Brocheré Grace Actor James Cromwell Dr. Arthur Arden Actor Jessica Lange Sister Jude Actor Ian McShane Leigh Emerson Guest Star Fredric Lehne Frank McCann Guest Star Britne Oldford Alma Walker Guest Star Barbara Tarbuck Mother Superior Claudia Guest Star Chris McGarry Mr. Lancaster Guest Star Lara Harris Rhonda Lancaster Guest Star Jennifer Holland Nurse Blackwell Guest Star Ryan Murphy Executive Producer Brad Falchuk Executive Producer Dante Di Loreto Executive Producer Tim Minear Executive Producer