In the Season 2 premiere, Mayor Kane's legacy is cemented with splendid groundbreaking ceremonies for the updated airport terminals. Though the sky seems the limit for his political future, his health continues to be an issue.

Kane uses a tragedy in his personal life to further his political agenda. He also tries to heal his fractured inner circle by poaching Mona Fredricks, the senior aide of his nemesis, and hiring ambitious newcomer Ian Todd, but can they fill the void left by Stone?

Kane's increasing infatuation with his new aide Mona leads him to get swept up in her enthusiasm for a housing-redevelopment project.

Kane attempts to clean house and deep-sixes longtime political cronies, while at home, Meredith and Emma want no part of a family reunion with him.

As Kane's symptoms begin to spiral out of control and he has problems telling the difference between his hallucinations and reality, the corruption sweep endangers his political power and his hold on city council.

Kane's maneuvers with the housing project lead to looting and rioting; later, he secretly attends an alternative clinic for treatment.

The alternative treatments appear to be working and Kane takes back control of the city, but in his efforts to fix his public perception, he may have to throw an old friend under the bus.

Kane reluctantly enters an alliance with a longtime foe on City Council, but he soon realizes that more serious measures must be undertaken to stave off bankruptcy.

Chicago's bankruptcy crisis means a loss of power for Kane as emergency measures are put in place, but threats by his enemies to expose him could be of even greater concern.

In the last episode of season two, Kane's mental faculties deteriorate further, and Sentinel editor Sam Miller gets ready to break a story that will destroy him. But, unknown to Kane, Kitty represents the true threat as she decides where her loyalties lie. As the odds stack up against him, Kane is forced to reveal the unthinkable to stay on top.