Calista Flockhart Kitty Walker Actor Rachel Griffiths Sarah Walker Actor Sally Field Nora Holden Actor Ron Rifkin Saul Holden Actor Patricia Wettig Holly Harper Actor Balthazar Getty Thomas Walker Actor Dave Annable Justin Walker Actor Matthew Rhys Kevin Walker Actor John Pyper-Ferguson Joe Whedon Actor Sarah Jane Morris Julia Walker Actor Ken Olin David Caplan Guest Star, Executive Producer Danny Glover Isaac Marshall Guest Star Steven Weber Graham Finch Guest Star Evie Peck Gail Guest Star Bruno Oliver Lab Technician Guest Star Jon Robin Baitz Executive Producer Marti Noxon Executive Producer David Marshall Grant Writer