Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Lindsay Price Kate Price Guest Star Megan Ward Annie Cartland Guest Star Eve Mauro Heather Marist Guest Star Kristen Kerr Brunette Victim Guest Star Emily Wilson Colette Guest Star Kevin Interdonato Garland Clarke Guest Star Michael Duisenberg Craig Tomlin Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Christopher Silber Writer Frederick E.O. Toye Director