Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Dr. Joan Watson Actor Aidan Quinn Capt. Tobias "Toby" Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Bill Heck Ty Morstan Guest Star Jennifer Ferrin Rebecca Ellison Guest Star Amy Landon Yvette Ellison Guest Star Asa Somers Doctor Guest Star Paul Michael Valley Burly Man Guest Star Casey Siemaszko Michael McGee Guest Star Ken Marks Moderator Guest Star Chris Bresky Recovering Addict Guest Star Rosa Arredondo Elaine Guest Star Rey Lucas Martin Guest Star Robert Doherty Executive Producer, Writer Sarah Timberman Executive Producer Carl Beverly Executive Producer Michael Cuesta Executive Producer John David Coles Director