Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Nelsan Ellis Shinwell Johnson Actor Matthew Del Negro Guest Star Lorenzo Pisoni Guest Star Lee Tergesen Guest Star Jacob Alexander Guest Star Simon Belz Guest Star Irungu Mutu Guest Star Antonio Edwards Suarez Guest Star Leopold Manswell Guest Star Bianca Amato Guest Star Robert Doherty Executive Producer, Writer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Jeffrey Paul King Writer Christine Moore Director