Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Trevor Einhorn Frederick Crane Guest Star Philip Casnoff Dr. Bernard Gadston Guest Star Jeff Perry John Clayton Guest Star Josh Wise Warren Clayton Guest Star Morgan Davis Amanda Guest Star Michael Vira Contestant Guest Star James Lew Security Guard Guest Star Naomi Judd Lillian Guest Voice David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Sheldon Epps Director Saladin K. Patterson Writer